Short and long term impact of adenotonsillectomy on the immune system.
نویسندگان
چکیده
UNLABELLED Palatine and pharyngeal tonsils are immune reactive lymphoid organs that manifest specific antibodies and B/T-cell activity to respond to a variety of antigens. They perform humoral and cellular immune functions. The possible effects of adenotonsillectomy upon the immune system remain controversial. OBJECTIVE To study the short and long-term impacts of tonsillectomy upon the cellular and humoral immunity of children. METHOD This longitudinal prospective study included 29 children referred to adenotonsillectomy for adenotonsillar hypertrophy. Serum IgA, IgM, and IgG and lymphocyte counts were analyzed at three points in time: before surgery, 1-2 months after surgery (short term), and 12-14 months after surgery (long term). RESULTS TCD4+ cell counts were significantly increased shortly after surgery. IgA and IgG values were significantly reduced in the long run, but were within normal ranges for this age group. CONCLUSION This study indicated that adenotonsillectomy does not pose negative short or long term impacts upon the cellular and humoral immunity of children submitted to the procedure.
منابع مشابه
بررسی غلظت گروه و زیرگروههای ایمنوگلوبولین و فنوتیپ لنفوسیتی در کودکان قبل و بعد از عمل برداشت آدنویید و لوزهها در مرکز تحقیقات گوش و حلق و بینی و سر و گردن بیمارستان حضرت رسول اکرم(ص)
Background & Aim: Chronic infection of tonsils in childhood is a leading cause of adeno-tonsillectomy. A question has been asked for a long time to find out whether there is any risk of immune impairment after adenotonsillectomy. Therefore, the present study was undertaken to evaluate immunologic parameters in children before and after adenoidectomy. Patients & Methods: In this cohort study...
متن کاملUnderpricing, Ownership and Liquidity of Initial Public Offers (IPO) and Their Impact on Performance of IPO Stocks in Equity Markets of India
Paper studies the impact of the liquidity, underpricing and ownership up on both the short term and long term performance of the Initial Public Offer (IPO) stocks in the equity markets of India. Empirical analysis is undertaken to study the impact of liquidity, underpricing and ownership on Performance of IPO stocks. Multiple regression analysis is undertaken for analyzing the impact. It is fou...
متن کاملIgM, IgG, IgA Serum Levels and Lymphocytes Count Before and After Adenotonsillectomy
Background: Tonsils and adenoids are involved in both local immunity and immune surveillance for the development of immune defense mechanisms. A number of investigators have found decreased immunoglobulin levels after adenotonsillectomy while others have failed to find significant changes. The effects of adenotonsillectomy on the cellular immunity of children have not been investigated extensiv...
متن کاملShort-term and Long-term Impact of Video-driven Metapragmatic Awareness Raising on Speech Act Production: A Case of Iranian Interme-diate EFL Learners
متن کامل
Analysis of oil price behavior in the short term and long term based on the strategy of producers
The strategy are in the planning of oil price changes in the short and long term. Therefore, producers should seek to analyze the behavior of crude oil prices in the short and long term in order to adjust their plans. the price level in the oil market is associated with high fluctuations, many producers in the market seek to reduce exchange risk. This article aims to analyze the behavior of oil...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Brazilian journal of otorhinolaryngology
دوره 79 1 شماره
صفحات -
تاریخ انتشار 2013